Paul Didion graduated The Ohio State University with a Doctor of Veterinary Medicine in 1951. Paul was born in Bellevue, Ohio on April 2, 1921 to August and Louise Didion. Paul attended Ohio University for his undergraduate degree beginning in 1940. His college career was interrupted by the onset of World War II, as Paul enlisted with the Marine Corps in 1942. Paul returned to Ohio in 1944 to complete his degree and begin veterinary school. Paul was a member of Beta Theta Pi fraternity, Omega Tau Sigma, veterinary medicine fraternity and the American Veterinary Medicine Association.
Following his graduation from OSU, Paul moved to Jefferson, Ohio with his college sweetheart, Lela. There he opened his first veterinary practice, specializing in agricultural livestock.